Iconeus Functional Ultrasound (fUS) preclinical imaging systems

Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.
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2011 — 2021

Functional ultrasound imaging: a new imaging modality for neuroscience

T. Deffieux, C. Demené, M. Tanter
Neuroscience, 2021, 474: 110-121, http://doi.org/10.1016/j.neuroscience.2021.03.005

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2021

Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging

N. Tournier, C. Comtat, V. Lebon, J.L. Gennisson
Neuroscience, 2020, 474: 80-93,. http://doi.org/10.1016/j.neuroscience.2020.10.015

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2020

Chronic imaging of mouse brain: From optical systems to functional ultrasound

K. Kılıç, J. Tang, Ş.E. Erdener, S. Sunil, J.T. Giblin, B.S. Lee, D.D. Postnov, A. Chen, D.A. Boas
Current Protocols in Neuroscience, 2020, 93:e98, http://doi.org/10.1002/cpns.98

  • Mouse
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Method
  • 2020

Early ultrafast ultrasound imaging of cerebral perfusion correlates with ischemic stroke outcomes and responses to treatment in mice

V. Hingot, C. Brodin, F. Lebrun, B. Heiles, A. Chagnot, M. Yetim, M. Gauberti, C. Orset, M. Tanter, O. Couture, T. Deffieux, D. Vivien
Theranostics, 2020, 10: 7480-7491, http://doi.org/10.7150/thno.44233

  • Mouse
  • Vascular imaging
  • Research article
  • 2020

Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors

A. Anfray, A. Drieu, V. Hingot, Y. Hommet, M. Yetim, M. Rubio, T. Deffieux, M. Tanter, C. Orset, D. Vivien
Journal of Cerebral Blood Flow & Metabolism, 2019, 40: 2038-2054, http://doi.org/10.1177/0271678X19883599

  • Mouse
  • Vascular imaging
  • Research article
  • 2019

A large aperture row column addressed probe for in vivo 4D ultrafast doppler ultrasound imaging

J. Sauvage, M. Flesch, G. Férin, Nguyen-A. Dinh, J. Porée, M. Tanter, M. Pernot, T. Deffieux
Physics in Medicine and Biology, 2018, 63: 215012, http://doi.org/10.1088/1361-6560/aae427

  • Human
  • Vascular imaging
  • Research article
  • 2018

Ultrafast doppler for neonatal brain imaging

C. Demené, J. Mairesse, J. Baranger, M. Tanter, O. Baud
Neuroimage, 2019, 185: 851-856, http://doi.org/10.1016/j.neuroimage.2018.04.016

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2019

Microvascular flow dictates the compromise between spatial resolution and acquisition time in ultrasound localization microscopy

V. Hingot, C. Errico, B. Heiles, L. Rahal, M. Tanter, O. Couture
Science Reports, 2019, 9: 2456, http://doi.org/10.1038/s41598-018-38349-x

  • Rat
  • Vascular imaging
  • Research article
  • 2019

Multi-parametric functional ultrasound imaging of cerebral hemodynamics in a cardiopulmonary resuscitation model

C. Demené, D. Maresca, M. Kohlhauer, F. Lidouren, P. Micheau, B. Ghaleh, M. Pernot, R. Tissier, M. Tanter
Science Reports, 2018, 8: 16436, http://doi.org/10.1038/s41598-018-34307-9

  • Mouse
  • Vascular imaging
  • Research article
  • 2018

Evidence from functional ultrasound imaging of enhanced contralesional microvascular response to somatosensory stimulation in acute middle cerebral artery occlusion/reperfusion in rats: A marker of ultra-early network reorganization?

C. Brunner, M. Korostelev, S. Raja, G. Montaldo, A. Urban, J.C. Baron
J. Cereb Blood Flow Metab. 2018, 38: 1690-1700, http://doi.org/10.1177/0271678X18786359

  • Rat
  • Vascular imaging
  • Research article
  • 2018
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