Functional ultrasound brain imaging is the next frontier in pre-clinical neuroscience. Iconeus, a Paris-based technological company, is introducing a breakthrough modality for preclinical imaging of brain activation, connectivity and vasculature, based on the measurement of minute changes in cerebral blood volume with ultra-high resolution and sensitivity.
Now you can observe the brain activity of awake animals in real time
Iconeus One is able to directly measure subtle variations in the blood volume of individual voxels in the whole rodent brain. This allows functional neuroimaging, which measures neuronal activation patterns through the neurovascular coupling, similarly to fMRI - but with significantly higher resolution and sensitivity.
Detection of minute blood flow changes in tiny vessels requires extreme sensitivity. Only Ultrasensitive Doppler combined with our patented ultrafast MPW™(MultiPlaneWave) technology – providing up to fifty thousand images per second – and optimized signal processing can reach this goal.