Iconeus One system
Iconeus One is the only full-featured acquisition system for pre-clinical functional ultrasound imaging of brain activity (fUS) and vasculature imaging. This breakthrough modality is based on the measurement of blood volume with an unprecedented ultra-high sensitivity.
With Iconeus One you can measure neuronal activation and connectivity – with higher sensitivity and resolution than with BOLD-based fMRI – in behaving or anesthetized animals.
Iconeus One draws on our patented multi-plane-wave™ ultrasound technology. Its ultra-fast frame rate allows the user to image neuronal activity through neurovascular coupling, while its ultra-high sensitivity makes it possible to directly measure subtle variations in the blood volume of individual voxels in the brain.
- Real time engine: Multi-plane-wave technology
- Spatial resolution: 100 × 100 × 400 μm at 15 MHz
- Temporal resolution: Down to 10 ms
- Awake kits: Rat, mouse and primate
- Robotic station for head-fixed animals: 4-axis high speed motorized platform
- Capacity: 10 TB, >25 Tflops
- Dimensions: l: 809,5 × L: 971 × D: 971
Ease of use
- No need for expertise in imaging technology
- "Plug and scan"
- User-friendly software with presets for rapid acquisition and processing
- Integrated 3D mouse brain atlas
- Compatible with other imaging modalities (EEG, optogenetics, etc.)
- Compact, wheeled imager
- On-site installation and support
- Unique microprobe design
- Awake, freely moving, resting-state and asleep conditions
- Rats, mice, birds, primates, ferrets, guinea pigs
Pharmacology & drug discoveryBetter than BOLD
Fundamental neuroscience researchMultimodal insight
Stroke and neurovascular researchTime is brain
For preclinical research, the portability and high versatility of our technology enables the study of brain activity at unprecedented scales and in a large variety of subject states:
- freely moving,
- and asleep conditions.
Our technology leverages more than 20 years of innovations in brain ultrasound imaging. Its history begins at the Langevin Institute (Paris, France), where the research team led by Prof. Mickael Tanter (Inserm, ESPCI Paris, CNRS) pioneered functional ultrasound neuroimaging and produced other major breakthroughs in biomedical echography.
Since 2011, we have been working intensively with neuroscientists to finely adapt our technology to their specific needs.
Our technology is protected by a strong patent portfolio to ensure the best quality and experience for our customers.