As beta tester, I had the opportunity to follow the maturation of Iconeus One, from an early version to the commercial product. Right from the beginning I was fascinated how little effort it takes to obtain activation maps of the mouse brain.
No long preparation time, just sedation and fixation of the animal, and the experiment can start.
Resolution is amazing – even small mouse brain regions are covered by several voxels. Brain regions can automatically be identified, and the software efficiently guides the positioning of the sensor head. This makes fUS an ideal tool for routine studies of the effects of compounds on brain network activity.