2D and 3D probes for functional ultrasound

What you get from fUS depends crucially on the specifications of the probe, and our probes will give you the best possible results for every application.

We offer three types of probes, described in more detail in the panels below:

• Linear probes: For high-sensitivity 2D imaging across a range of applications
• Multiarray probes: For fast and detailed 3D imaging of small rodent brains
• RCA probes: For maximum resolution and dynamic brain imaging capability.

All are designed exclusively for our Iconeus One platform, and are equipped with optimized electronics that ensure maximum contrast and eliminate electrical noise from other lab equipment, providing you with the clearest images possible.

Our linear probes offer a range of frequency options and element counts, enabling you to accommodate different imaging depths and field widths, while providing excellent sensitivity for a range of applications.

When coupled with our motorized scanning platform, they can also image 3D volumes by rapidly ‘stepping’ across the scan area (with a trade-off in time resolution as the number of steps increases).

Our linear probes are ideal when you:

• Are focused on high-sensitivity, high-resolution 2D imaging
• Would like the ability to carry out 3D imaging, but don’t need high time resolution
• Need a versatile probe for a variety of research applications.

Our patented IcoPrime-4D MultiArray probe uses ‘simultaneous multislicing’ to acquire four 2D image ‘slices’ of the brain at once, before being moved stepwise across the scanning surface, where the process is repeated.

This allows you to benefit from brain-wide coverage and high time resolution for small rodent brains, without compromising sensitivity.

IcoPrime-4D MultiArray is ideal when you:

• Routinely carry out 3D imaging in the whole brains of head-fixed mice
• Need high temporal resolution (e.g. for resting-state functional connectivity studies)
• Require a high-sensitivity probe suitable for the most advanced neuroimaging studies.

IcoPrime-4D RCA probe is a row-column addressed (RCA) probe that provides rapid acquisition and a 1 cm³  field of view – all in a compact design that is suitable for various experimental setups.

Not only that, but it uses patented XDoppler technology to overcome the problems with sidelobe artifacts and limited contrast encountered with conventional RCA probes. This makes it an excellent choice for detailed and/or dynamic studies – opening the door to the next generation of ultrasound brain imaging.

The IcoPrime-4D RCA probe is ideal when you:

• Want to capture super-resolution 3D images of the whole mouse brain (or partial brain volumes in other animals) using our 3D ULM technology
• Are studying dynamic processes and need to capture real-time changes in brain activity at high framerate and with isotropic resolution
• Are able to use either a cranial window or microbubble contrast agents.

Choosing the right probe for an application involves weighing up a number of factors, which can be a bit complicated. So we’re happy to talk to you about your work, to fully understand your application and ensure that the probe you select is perfectly matched to your requirements.

So when you’re ready, please give us a call for more information on technical specifications.