Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

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Year
MethodPublished in 2025

PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging

Nicolas Zucker, Samuel Le Meur-Diebolt, Felipe Cybis Pereira, Jerome Baranger, Isabella Hurvitz,  Charlie Demené, Bruno Osmanski,  Nathalie Ialy-Radio, Valérie Biran, Olivier Baud, Sophie Pezet, Thomas Deffieux, Mickael Tanter

Application:
Functional neuroimaging
Model:
Mouse
Research articlePublished in 2025

Hierarchical encoding of natural sounds mixtures in ferret auditory cortex

Agnès Landemard,   Célian Bimbard,  Yves Boubenec doi: https://doi.org/10.1101/2025.02.15.637892 bioRxiv

Application:
Functional neuroimaging
Model:
Ferret
Research articlePublished in 2025

Temporal-Coherence Induces Binding of Responses to Sound Sequences in Ferret Auditory Cortex

Kai Lu, Kelsey Dutta, Ali Mohammed, Mounya Elhilali, Shihab Shammahttps://doi.org/10.1016/j.isci.2025.111991 iScience

Application:
Neuropharmacology
Model:
Ferret
Research articlePublished in 2025

Western diet since adolescence impairs brain functional hyperemia at adulthood in mice: rescue by a balanced ω-3: ω-6polyunsaturated fatty acids ratio International Journal of Obesity 

Haleh Soleimanzad, Clémentine Morisset, Mireia Montaner, Frédéric Pain, Christophe Magnan, Mickaël Tanter and Hirac Gurden

Application:
Functional neuroimaging
Model:
Mouse
Research articlePublished in 2024

Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopy

Mickaël Pereira, Marine Droguerre, Marco Valdebenito, Louis Vidal, Guillaume Marcy, Sarah Benkeder, Jean-Christophe Comte, Olivier Pascual, Luc Zimmer,  View ORCID ProfileBenjamin Vidal doi: https://doi.org/10.1101/2024.12.13.628348 bioRxiv

Application:
Vascular imaging
Model:
Human
Research articlePublished in 2024

Induction of hemodynamic traveling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging

Mickaël Pereira, Marine Droguerre, Marco Valdebenito, Louis Vidal, Guillaume Marcy, Sarah Benkeder, Jean-Christophe Comte, Olivier Pascual, Luc Zimmer,  View ORCID ProfileBenjamin Vidal doi: https://doi.org/10.1101/2024.12.13.628348 bioRxiv

Application:
Functional neuroimaging
Model:
Rat
Research articlePublished in 2024

Premotor cortex hemodynamics reflect internal auditory category, not reported category

Jeff Boucher, Shihab Shamma, Yves Boubenec https://doi.org/10.1101/2024.12.18.628869 bioRxiv

Application:
Functional neuroimaging
Model:
Ferret
MethodPublished in 2024

Novel intravital approaches to quantify deep vascular structure and perfusion in the aging mouse brain using ultrasound localization microscopy (ULM).

Nyúl-Tóth Á, Negri S, Sanford M, Jiang R, Patai R, Budda M, Petersen B, Pinckard J, Chandragiri SS, Shi H, Reyff Z, Ballard C, Gulej R, Csik B, Ferrier J, Balasubramanian P, Yabluchanskiy A, Cleuren A, Conley S, Ungvari Z, Csiszar A, Tarantini S. J Cereb Blood Flow Metab. 2024 Nov;44(11):1378-1396. doi: 10.1177/0271678X241260526.

Application:
ULM
Model:
Mouse
Research articlePublished in 2024

Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging

Diana A Liao, Eva Schwarzbach, Andreas Nieder doi: https://doi.org/10.1101/2024.11.26.625563 – bioRxiv

Application:
Functional neuroimaging
Model:
Crows
Research articlePublished in 2024

Functional Ultrasound Imaging Reveals Activation Properties of Clinical Spinal Cord Stimulation Therapy Stimulation Programming

Koeun Lim, P Sean Slee, Andrew Kibler, Steven Falowski, Kasra Amirdelfan doi: https://doi.org/10.1101/2024.10.22.619739 – bioRxiv

Application:
Vascular imaging
Model:
Ovine