Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

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Year
Research articlePublished in 2022

Ultrafast Doppler imagingand ultrasound localizationmicroscopy reveal the complexityof vascular rearrangementin chronic spinal lesion

Beliard, B., Ahmanna, C., Tiran, E. et al. 

Application:
Functional neuroimaging
Model:
Rat
Research articlePublished in 2025

Speed Vascular Patterns in the Spatial Navigation System

Felipe Cybis Pereira, Sebastian H. Castedo, Samuel Le Meur-Diebolt, Nathalie Ialy-Radio, Soumee Bhattacharya, Jeremy Ferrier, Bruno Félix Osmanski, Simona Cocco, RemiMonasson, Sophie Pezet, Mickaël Tanter

Application:
Functional neuroimaging
Model:
Rat
Research articlePublished in 2023

Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration

Sara Cadoni, Charlie Demené,Ignacio Alcala, Matthieu Provansal,Diep Nguyen,Dasha Nelidova, Guillaume Labernède, Jules Lubetzki, Ruben Goulet, Emma Burban, Julie Dégardin, Manuel Simonutti, Gregory Gauvai ,Fabrice Arcizet, Olivier Marre, Deniz Dalkara, Botond Roska, José Alain Sahel, Mickael Tanter & Serge Picaud

Application:
Functional neuroimaging
Model:
Mouse
MethodPublished in 2025

Capillary-scale Microvessel Imaging with High-frequency Ultrasound Localization Microscopy in Mouse Brain.

Lowerison MR, Wang Y, Lin BZ, Huang Z, Yan D, Shin Y, Song P.

Application:
ULM
Model:
Mouse
MethodPublished in 2025

Computationally Efficient SVD Filtering for Ultrasound Flow Imaging and Real-Time Application to Ultrafast Doppler.

Pialot B, Guidi F, Bonciani G, Varray F, Tortoli P, Ramalli A

Application:
Functional neuroimaging
MethodPublished in 2025

3D ultrasound localization microscopy of the nonhuman primate brain.

Xing P, Perrot V, Dominguez-Vargas AU, Porée J, Quessy S, Dancause N, Provost J.

Application:
ULM
Model:
Non-Human Primate
Research articlePublished in 2025

Non-invasive 4D transcranial functional ultrasound and ultrasound localization microscopy for multimodal imaging of neurovascular response.

Jones RM, DeRuiter RM, Lee HR, Munot S, Belgharbi H, Santibanez F, Favorov OV, Dayton PA, Pinton GF.

Application:
ULM
Model:
Mouse
Research articlePublished in 2025

Non-invasive volumetric ultrasound localization microscopy detects vascular changes in mice with Alzheimer’s disease.

Jones RM, DeRuiter RM, Deshmukh M, Dayton PA, Pinton GF.

Application:
ULM
Model:
Mouse
Research articlePublished in 2025

Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage.

Lin BZ, Fan AC, Wang Y, Lowerison MR, Dong Z, You Q, Sekaran NVC, Llano D, Borden M, Song P.

Application:
ULM
Model:
Mouse
Research articlePublished in 2025

Western diet since adolescence impairs brain functional hyperemia at adulthood in mice: rescue by a balanced ω-3: ω-6polyunsaturated fatty acids ratio International Journal of Obesity

Haleh Soleimanzad, Clémentine Morisset, Mireia Montaner, Frédéric Pain, Christophe Magnan, Mickaël Tanter and Hirac Gurden

Application:
Functional neuroimaging
Model:
Mouse
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