Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

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Year
Research articlePublished in 2024

Characterizing defective lipid metabolism in the lateral septum of mice treated with olanzapine: implications for its side effects

Lixuan Huang, Ying Sun, Chao Luo, Wei Wang,  Si Shi, Genmin Sun, Peijun Ju, Jianhua Chen Front Pharmacol. 2024 Jun 14;15:1419098. doi: 10.3389/fphar.2024.1419098

Application:
Neuropharmacology
Model:
Mouse
Research articlePublished in 2024

Theta-frequency medial septal nucleus deep brain stimulation increases neurovascular activity in MK-801-treated mice

Lindsey M Crown, Kofi A Agyeman, Wooseong Choi, Nancy Zepeda, Ege Iseri, Pooyan Pahlavan, Steven J Siegel, Charles Liu, Vasileios Christopoulos, Darrin J Lee Front Neurosci. 2024 Mar 15;18:1372315. doi: 10.3389/fnins.2024.1372315

Application:
Functional neuroimaging
Model:
Mouse
Research articlePublished in 2024

Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice

Ioannis Mantas, Ivana Flais, Yuvarani Masarapu, Tudor Ionescu, Solène Frapard, Felix Jung, Pierre Le Merre, Marcus Saarinen, Katarina Tiklova, Behzad Yaghmaeian Salmani, Linda Gillberg, Xiaoqun Zhang, Karima Chergui, Marie Carlén, Stefania Giacomello, Bastian Hengerer, Thomas Perlmann, Per Svenningsson  doi: 10.1038/s41467-024-52429-9 – Nature Communications volume 15, Article number: 8176 (2024) Published 18 September 2024

Application:
Resting-state functional connectivity
Model:
Mouse
MethodPublished in 2024

Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles

Ge Zhang, Mathis Vert, Mohamed Nouhoum, Esteban Rivera, Nabil Haidour, Anatole Jimenez, Thomas Deffieux, Simon Barral, Pascal Hersen, Claire Rabut, Mikhail Shapiro, Mickael Tanter doi: https://doi.org/10.1101/2024.10.14.618186 – bioRxiv

MethodPublished in 2024

PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging

Nicolas Zucker, Samuel Le Meur-Diebolt, Felipe Cybis Pereira, Jerome Baranger, Isabella Hurvitz,  Charlie Demené, Bruno Osmanski,  Nathalie Ialy-Radio, Valérie Biran, Olivier Baud, Sophie Pezet, Thomas Deffieux, Mickael Tanter doi: https://doi.org/10.1101/2024.09.22.614324 – bioRxiv

Application:
Vascular imaging
Model:
Mouse
Research articlePublished in 2024

The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice

Martin Pedard, Lucie Prevost, Camille Carpena, Brian Holleran, Laurence Desrues, Martine Dubois, Celeste Nicola, Roxane Gruel, David Godefroy, Thomas Deffieux, Mickael Tanter, Carine Ali, Richard Leduc, Laurent Prézeau, Pierrick Gandolfo, Fabrice Morin, Olivier Wurtz, Thomas Bonnard, Denis Vivien & Hélène Castel  DOI https://doi.org/10.1038/s41467-024-52654-2 – Nature Communications volume 15, Article number: 8430 (2024) 

Application:
Vascular imaging
Model:
Mouse
Research articlePublished in 2024

Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer’s disease: correlation with pathological impairments 

Haoming Lin, Zidan Wang, Yingtao Liao, Zhifan Yu, Huiqin Xu, Ting Qin, Jianbo Tang, Xifei Yang, Siping Chen, Xin Chen, Xinyu Zhang, and Yuanyuan Shena eBioMedicine 2024;108: 105355 Published Online 17 September 2024 https://doi.org/10. 1016/j.ebiom.2024. 105355 

Application:
Vascular imaging
Model:
Mouse
MethodPublished in 2024

Transcranial Brain-Wide Functional Ultrasound and Ultrasound Localization Microscopy in Mice using Multilinear Probes

Mathis Vert, Ge Zhang, Adrien Bertolo, Nathalie Ialy-Radio, Sophie Pezet, Bruno Osmanski, Thomas Deffieux, Mohamed Nouhoum, Mickael Tanter doi: https://doi.org/10.1101/2024.10.29.620796 -bioRxiv

Application:
Functional neuroimaging
Model:
Mouse
Research articlePublished in 2024

Functional ultrasound neuroimaging reveals mesoscopic organization of saccades in the lateral intraparietal area of posterior parietal cortex.

Griggs WS, Norman SL, Tanter M, Liu C, Christopoulos V, Shapiro MG, Andersen RA.  doi: 10.1101/2024.06.28.600796. 2024 Jul 2 – bioRxiv

Application:
Functional neuroimaging
Model:
Non-Human Primate
Research articlePublished in 2024

Neurovascular coupling and CO2 interrogate distinct vascular regulations

Tournissac M, Chaigneau E, Pfister S, Aydin AK, Goulam Houssen Y, O’Herron P, Filosa J, Collot M, Joutel A, Charpak S. Nat Commun. 2024 Sep 2;15(1):7635. doi: 10.1038/s41467-024-49698-9.

Application:
Vascular imaging
Model:
Mouse
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