Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

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Model

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Application

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Type

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Year
MethodPublished in 2024

Comparison of image registration techniques in functional ultrasound imaging

Shan Zhong, Kofi Agyeman, Shanze Syed, Richard Tobing, Wooseong Choi, Charles Liu, Darrin Lee, Vassilios Christopoulos doi: https://doi.org/10.1101/2023.09.15.557999 – bioRxiv

Application:
Vascular imaging
Model:
Mouse
Research articlePublished in 2024

Development of a novel, non-invasive and whole brain biomarker of demyelination in a mouse model of multiple sclerosis

Benoit Beliard, Lauriane Delay, Isabelle Rivals, Youenn Travert-Jouanneau, Nathalie Ialy-Radio, Annabelle Réaux-Le Goazigo, Thomas Deffieux, Daniel P. Bradley, Mickael Tanter, Sophie Pezet doi: https://doi.org/10.1101/2024.03.18.585596 – bioRxiv

Application:
Neuropharmacology
Model:
Mouse
Research articlePublished in 2024

Opioid-Induced Inter-regional Dysconnectivity Correlates with Analgesia in Awake Mouse Brains

Jean-Charles Mariani, Samuel Diebolt, Laurianne Beynac, Renata Santos, Stefan Schulz, Thomas Deffieux, Mickael Tanter,  Zsolt Lenkei, Andrea Kliewer doi: https://doi.org/10.1101/2024.07.30.604249 – bioRxiv

Application:
Neuropharmacology
Model:
Mouse
Research articlePublished in 2024

Temporal-Coherence Induces Binding of Responses to Sound Sequences in Ferret Auditory Cortex

Kai Lu, Kelsey Dutta, Ali Mohammed, Mounya Elhilali, Shihab Shamma doi: https://doi.org/10.1101/2024.05.21.595170 – bioRxiv

Application:
Functional neuroimaging
Model:
Ferret
MethodPublished in 2024

The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice

Bradley J. Edelman, Dominique Siegenthaler, Paulina Wanken, Bethan Jenkins, Bianca Schmid, Andrea Ressle, Nadine Gogolla, Thomas Frank, Emilie Macé  PLoS Biol 22(6):  https://doi.org/10.1371/journal.pbio.3002664 Published: June 3, 2024

Application:
Functional neuroimaging
Model:
Mouse
Research articlePublished in 2024

Functional ultrasound imaging of human brain activity through an acoustically transparent cranial window

Claire Rabut, Sumner L Norman, Whitney S Griggs, Jonathan J Russin, Kay Jann, Vasileios Christopoulos, Charles Liu, Richard A Andersen, Mikhail G Shapiro doi: 10.1126/scitranslmed.adj3143 – Sci Transl Med. 2024 May 29;16(749):eadj3143 Update of: A window to the brain: ultrasound imaging of human neural activity through a permanent acoustic window. Rabut C, Norman SL, Griggs WS, […]

Application:
Functional neuroimaging
Model:
Human
Research articlePublished in 2024

Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction

Marion Ponserre, Tudor M. Ionescu, Alessa A. Franz, Serena Deiana, Niklas Schuelert, Thorsten Lamla, Rhîannan H. Williams, Carsten T. Wotjak, Scott Hobson, Julien Dine, Azar Omrani  https://doi.org/10.1016/j.neuropharm.2024.109970 – Neuropharmacology Volume 254, 15 August 2024, 109970

Application:
Resting-state functional connectivity
Model:
Mouse
Research articlePublished in 2024

Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization

Nadine Felizitas Binder, Mohamad El Amki, Chaim Glück, William Middleham, Anna Maria Reuss, Adrien Bertolo, Patrick Thurner, Thomas Deffieux, Chryso Lambride, Robert Epp, Hannah-Lea Handelsmann, Philipp Baumgartner, Cyrille Orset, Philipp Bethge, Zsolt Kulcsar, Adriano Aguzzi, Mickael Tanter, Franca Schmid, Denis Vivien, Matthias Tasso Wyss, Andreas Luft, Michael Weller, Bruno Weber, Susanne Wegener 2024 May 1;112(9):1456-1472.e6. […]

Application:
Vascular imaging
Model:
Mouse
Research articlePublished in 2023

Human brain mapping using co-registered fUS, fMRI and ESM during awake brain surgeries: A proof-of-concept study.

Soloukey S, Collée E, Verhoef L, Satoer DD, Dirven CMF, Bos EM, Schouten JW, Generowicz BS, Mastik F, De Zeeuw CI, Koekkoek SKE, Vincent AJPE, Smits M, Kruizinga P. Human brain mapping using co-registered fUS, fMRI and ESM during awake brain surgeries: A proof-of-concept study. Neuroimage. 2023 Dec 1;283:120435. doi: 10.1016/j.neuroimage.2023.120435. Epub 2023 Oct 30. 

Application:
Functional neuroimaging
Model:
Human
MethodPublished in 2023

Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging.

Generowicz BS, Dijkhuizen S, Bosman LWJ, De Zeeuw CI, Koekkoek SKE, Kruizinga P. Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2023 Dec;70(12):1726-1738. doi:10.1109/TUFFC.2023.3330343. Epub 2023 Dec 14.

Application:
Functional neuroimaging
Model:
Mouse
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