Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

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Model

Model

Application

Application

Type

Type

Year

Year
Method

Time-lagged Functional Ultrasound for Multi- parametric Cerebral Hemodynamic Imaging.

Liu B, Wang Y, Fomin-Thunemann N, Thunemann M, Kilic K, Devor A, Cheng X, Tan J, Jiang J, Boas DA, Tang J. Time-lagged Functional Ultrasound for Multi-parametric Cerebral Hemodynamic Imaging. IEEE Trans Med Imaging. 2023 Sep 13;PP. doi: 10.1109/TMI.2023.3314734. Epub ahead of print.

Application:
Vascular imaging
Model:
Mouse
MethodPublished in 2023

Case report: High-resolution, intra-operative µDoppler-imaging of spinal cord hemangioblastoma.

Soloukey S, Verhoef L, Generowicz BS, De Zeeuw CI, Koekkoek SKE, Vincent AJPE, Dirven CMF, Harhangi BS, Kruizinga P. Case report: High-resolution, intra-operative µDoppler-imaging of spinal cord hemangioblastoma. Front Surg. 2023 Jun 5;10:1153605. doi: 10.3389/fsurg.2023.1153605.

Application:
Vascular imaging
Model:
Human
MethodPublished in 2023

Microscale acoustic metamaterials as conformal sonotransparent skull prostheses.

Kim G, Rabut C, Ling B, Shapiro M, Daraio C. Microscale acoustic metamaterials as conformal sonotransparent skull prostheses. Res Sq [Preprint]. 2023 May 10:rs.3.rs-2743580. doi: 10.21203/rs.3.rs-2743580/v1.

Application:
Resting-state functional connectivity
Model:
Mouse
MethodPublished in 2023

Filler-Enhanced Piezoelectricity of Poly-L-Lactide and Its Use as a Functional Ultrasound-Activated Biomaterial.

Vukomanović M, Gazvoda L, Kurtjak M, Maček-Kržmanc M, Spreitzer M, Tang Q, Wu J, Ye H, Chen X, Mattera M, Puigmartí-Luis J, Pane SV. Filler-Enhanced Piezoelectricity of Poly-L-Lactide and Its Use as a Functional Ultrasound-Activated Biomaterial. Small. 2023 Aug;19(35):e2301981. doi:10.1002/smll.202301981.

Application:
Resting-state functional connectivity
Research articlePublished in 2023

Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.

Brunner C, Denis NL, Gertz K, Grillet M, Montaldo G, Endres M, Urban A. Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke. J Cereb Blood Flow Metab. 2024 Jan;44(1):6-18. doi: 10.1177/0271678X231191600.

Application:
Vascular imaging
Model:
Rat
Research articlePublished in 2022

In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy.

Demeulenaere O, Bertolo A, Pezet S, Ialy-Radio N, Osmanski B, Papadacci C, Tanter M, Deffieux T, Pernot M. In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy. EBioMedicine. 2022 May;79:103995. http://doi: 10.1016/j.ebiom.2022.103995.

Application:
Vascular imaging
Model:
Mouse
Research articlePublished in 2022

Type 2 diabetes albuminuric and non-albuminuric phenotypes have different morphological and functional ultrasound features of diabetic kidney disease.

Garofolo M, Napoli V, Lucchesi D, Accogli S, Mazzeo ML, Rossi P, Neri E, DelPrato S, Penno G. Type 2 diabetes albuminuric and non-albuminuric phenotypes have different morphological and functional ultrasound features of diabetic kidney disease. Diabetes Metab Res Rev. 2023 Jan;39(1):e3585. https://doi:10.1002/dmrr.3585.

Application:
Vascular imaging
Model:
Human
ReviewPublished in 2022

The developments and applications of functional ultrasound imaging.

Huang L, He Q, Wang R, Wei X, Xie G, Luo J.[The developments and applications of functional ultrasound imaging]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2022 Oct 25;39(5):1015-1021. Chinese. https://doi: 10.7507/1001-5515.202206050.

Application:
Resting-state functional connectivity
ReviewPublished in 2021

Functional ultrasound imaging: a new imaging modality for neuroscience

T. Deffieux, C. Demené, M. Tanter Neuroscience, 2021, 474: 110-121, http://doi.org/10.1016/j.neuroscience.2021.03.005

Application:
Resting-state functional connectivity
Model:
Bird
ReviewPublished in 2020

Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging

N. Tournier, C. Comtat, V. Lebon, J.L. Gennisson Neuroscience, 2020, 474: 80-93,. http://doi.org/10.1016/j.neuroscience.2020.10.015

Application:
Resting-state functional connectivity
Model:
Mouse
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