Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.

2011 — 2024

Enhancement of Mediodorsal Thalamus Rescues Aberrant Belief Dynamics in a Novel Mouse Model for Schizophrenia.

Zhou T, Ho YY, Lee RX, Fath AB, He K, Scott J, Bajwa N, Hartley ND, Wilde J, Gao X, Li C, Hong E, Nassar MR, Wimmer RD, Singh T, Halassa MM, Feng G. Enhancement of Mediodorsal Thalamus Rescues Aberrant Belief Dynamics in a Novel Mouse Model for Schizophrenia. bioRxiv [Preprint]. 2024 Jan 9:2024.01.08.574745. doi: 10.1101/2024.01.08.574745.

Functional Cerebral Neurovascular Mapping During Focused Ultrasound Peripheral Neuromodulation of Neuropathic Pain.

Lee SA, Kamimura HAS, Smith M, Konofagou EE. Functional Cerebral Neurovascular Mapping During Focused Ultrasound Peripheral Neuromodulation of Neuropathic Pain. IEEE Trans Biomed Eng. 2024 Jan 10;PP. doi:10.1109/TBME.2024.3352025. Epub ahead of print.

Specific and non-uniform brain states during cold perception in mice.

Koorliyil H, Sitt J, Rivals I, Liu Y, Bertolo A, Cazzanelli S, Dizeux A, Deffieux T, Tanter M, Pezet S. Specific and non-uniform brain states during cold perception in mice. J Neurosci. 2024 Jan 5:e0909232023. doi:10.1523/JNEUROSCI.0909-23.2023. Epub ahead of print.

Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements.

Franx BA, Lebrun F, Chin Joe Kie L, Deffieux T, Vivien D, Bonnard T, Dijkhuizen RM; CONTRAST consortium. Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements. J Cereb Blood Flow Metab. 2023 Dec 21:271678X231220698. doi:10.1177/0271678X231220698. Epub ahead of print.

Circuit mechanism for suppression of frontal cortical ignition during NREM sleep.

Li B, Ma C, Huang YA, Ding X, Silverman D, Chen C, Darmohray D, Lu L, Liu S, Montaldo G, Urban A, Dan Y. Circuit mechanism for suppression of frontal cortical ignition during NREM sleep. Cell. 2023 Dec 21;186(26):5739-5750.e17. doi: 10.1016/j.cell.2023.11.012. Epub 2023 Dec 8.

Chronic brain functional ultrasound imaging in freely moving rodents performing cognitive tasks.

El Hady A, Takahashi D, Sun R, Akinwale O, Boyd-Meredith T, Zhang Y, Charles AS, Brody CD. Chronic brain functional ultrasound imaging in freely moving rodents performing cognitive tasks. J Neurosci Methods. 2023 Dec 4;403:110033. doi: 10.1016/j.jneumeth.2023.110033. Epub ahead of print.

Decoding motor plans using a closed-loop ultrasonic brain-machine interface.

Griggs WS, Norman SL, Deffieux T, Segura F, Osmanski BF, Chau G, Christopoulos V, Liu C, Tanter M, Shapiro MG, Andersen RA. Decoding motor plans using a closed-loop ultrasonic brain-machine interface. Nat Neurosci. 2024 Jan;27(1):196-207. doi: 10.1038/s41593-023-01500-7. Epub 2023 Nov 30.

Functional ultrasound imaging of stroke in awake rats.

Brunner C, Montaldo G, Urban A. Functional ultrasound imaging of stroke in awake rats. Elife. 2023 Nov 21;12:RP88919. doi: 10.7554/eLife.88919.

Dissecting Multiparametric Cerebral Hemodynamics using Integrated Ultrafast Ultrasound and Multispectral Photoacoustic Imaging.

Chen H, Mirg S, Gaddale P, Agrawal S, Li M, Nguyen V, Xu T, Li Q, Liu J, Tu W, Liu X, Drew PJ, Zhang N, Gluckman BJ, Kothapalli SR. Dissecting Multiparametric Cerebral Hemodynamics using Integrated Ultrafast Ultrasound and Multispectral Photoacoustic Imaging. bioRxiv [Preprint]. 2023 Nov 11:2023.11.07.566048. doi: 10.1101/2023.11.07.566048.

Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging.

Generowicz BS, Dijkhuizen S, Bosman LWJ, De Zeeuw CI, Koekkoek SKE, Kruizinga P. Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2023 Dec;70(12):1726-1738. doi:10.1109/TUFFC.2023.3330343. Epub 2023 Dec 14.

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