Iconeus Functional Ultrasound (fUS) preclinical imaging systems

Publications on functional ultrasound

For over 10 years, researchers around the world and Iconeus engineers have been developing the technology of functional ultrasound, and using it to gain interesting insights into brain function. Many of their results have been published in high-profile journals such as Nature, Science Translational Medicine and Neuron.

Below you’ll find a comprehensive (but not exhaustive) list of publications covering all aspects of functional ultrasound.
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2011 — 2021

Functional ultrasound imaging: a new imaging modality for neuroscience

T. Deffieux, C. Demené, M. Tanter
Neuroscience, 2021, 474: 110-121, http://doi.org/10.1016/j.neuroscience.2021.03.005

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2021

Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging

N. Tournier, C. Comtat, V. Lebon, J.L. Gennisson
Neuroscience, 2020, 474: 80-93,. http://doi.org/10.1016/j.neuroscience.2020.10.015

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2020

Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice

C. Rabut, J. Ferrier, A. Bertolo, B. Osmanski, X. Mousset, S. Pezet, T. Deffieux, Z. Lenkei, M. Tanter
Neuroimage, 2020, 222: 117231, http://doi.org/10.1016/j.neuroimage.2020.117231

  • Mouse
  • Neuropharmacology
  • Research article
  • 2020

Chronic imaging of mouse brain: From optical systems to functional ultrasound

K. Kılıç, J. Tang, Ş.E. Erdener, S. Sunil, J.T. Giblin, B.S. Lee, D.D. Postnov, A. Chen, D.A. Boas
Current Protocols in Neuroscience, 2020, 93:e98, http://doi.org/10.1002/cpns.98

  • Mouse
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Method
  • 2020

Ultrafast doppler for neonatal brain imaging

C. Demené, J. Mairesse, J. Baranger, M. Tanter, O. Baud
Neuroimage, 2019, 185: 851-856, http://doi.org/10.1016/j.neuroimage.2018.04.016

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2019

Functional ultrasound neuroimaging: A review of the preclinical and clinical state of the art

T. Deffieux, C. Demene, M. Pernot, M. Tanter
Current Opinion in Neurobiology, 2018, 50: 128-135, http://doi.org/10.1016/j.conb.2018.02.001

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2018

Ultrafast imaging in biomedical ultrasound [Review]

M. Tanter, M. Fink
IEE.E. Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2014, 61: 102-119, http://doi.org/10.1109/TUFFC.2014.6689779

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2014

Functional ultrasound imaging of the brain: Theory and basic principles

E. Mace, G. Montaldo, B.F. Osmanski, I. Cohen, M. Fink, M. Tanter
IEE.E. Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2013, 60: 492-506 http://doi.org/10.1109/TUFFC.2013.2592

  • Mouse, Rat, Bird, Ferret, Swine, Non-Human Primate, Human
  • Resting-state functional connectivity, Functional neuroimaging, Vascular imaging, Neuropharmacology
  • Review
  • 2013

Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine

B. Vidal, M. Droguerre, L. Venet, L. Zimmer, M. Valdebenito, F. Mouthon, M. Charvériat
Neuropharmacology, 2020, 179: 108273, http://doi.org/10.1016/j.neuropharm.2020.108273

  • Rat
  • Neuropharmacology
  • Research article
  • 2020

Pharmaco-fUS for characterizing drugs for Alzheimer’s disease – The case of THN201, a drug combination of Donepezil plus Mefloquine

B. Vidal, M. Droguerre, M. Valdebenito, L. Zimmer, M. Hamon, F. Mouthon, M. Charvériat
Frontiers in Neuroscience, 2020, 14, https://doi.org/10.3389/fnins.2020.00835

  • Rat
  • Neuropharmacology
  • Research article
  • 2020
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