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Posts by category

• Category: Collaborations
  • ICONEUS ONE is now listed at UNIHA, the largest GPO (Group Purchasing Organization) in the field of medical devices, in France.
  • Iconeus to assist project on childhood neurodevelopment
  • Iconeus completes assembly of the first Iconeus One functional ultrasound system for clinical research
  • Major EU funding award opens prospect of functional ultrasound in humans with microscopic resolution
  • Iconeus joins project to facilitate research into brain injury in premature infants
• Category: Events
  • Iconeus to present functional Ultrasound at SfN 2024 in Chicago
  • First MINISYMPOSIA on fUS Imaging at SfN 2024
  • Iconeus to present latest fUS advances at the FENS Forum 2024
  • World Autism Awareness Day: Iconeus co-founder interviewed about early diagnosis of ASD
  • Meet Iconeus at AD/PD 2024 in Portugal
  • Webinar-Functional Ultrasound Neuroimaging : Principles, Applications & Perspectives
  • Iconeus to launch breakthrough probe for volumetric fUS imaging at SfN neuroscience conference 2023
  • Iconeus co-founder to speak at Panta Rei symposium
  • Meet Iconeus at Brain & Brain PET 2023
  • Iconeus sponsors functional microcirculation symposium
  • Iconeus to sponsor LEARNMEM 2023
  • Join us at EMIM 2023
  • Webinar: Multimodal neuroimaging using functional ultrasound
  • Iconeus to demonstrate fUS equipment at the first ISBUS conference
  • Iconeus to highlight fUS advances at SfN conference 2022
  • Meet Iconeus at ESM-Coimbra2022 in Portugal
  • Iconeus to exhibit at the FENS Forum 2022
  • fUSbrain 2022: Conference highlights from Corsica
  • Countdown to fUSbrain 2022
  • Join us at the ISMRM–ESMRMB conference in London
  • Webinar: Insights into stroke and neurovascular diseases using in vivo imaging
  • fUSbrain2022: Conference Scholarship Poster Competition opens for entries
  • Come and visit Iconeus at the FENS 2020 Virtual Forum!
  • Functional ultrasound experts meet at the first fUSBrain conference
• Category: New features
  • Iconeus’ 3D ULM technology used to image the mouse brain with microscale resolution
  • Developing a ‘GPS for the brain’ using functional ultrasound
  • Now available: Protocols for mouse brain imaging using Iconeus One
  • Gold-standard ‘brain GPS’ now included in the Iconeus One system
• Category: Science
  • First study published on clinical use of Iconeus fUS equipment
  • New research using fUS uncovers role of minor blood vessels on the success of ischemic stroke treatment
  • Iconeus software aids development of fUS-driven brain–machine interfaces
  • Highly sensitive, non-invasive functional connectivity mapping in the mouse brain using simultaneous multi-slice fUS imaging
  • First publication on ‘functional ULM’ reveals brain-wide neurovascular activity with high resolution
  • fUS Imaging reveals the dynamics of brain states in newborns
  • Three peer-reviewed studies validate the use of fUS for neuropharmacological studies
  • Key publications by Iconeus founders highlight major advances in fUS methodology and applications
  • fUS Experts share views on the future of multidimensional imaging
• Category: Staff
  • Iconeus hires quality and regulatory affairs manager in readiness for clinical applications
  • Three new staff members join Iconeus
  • New Application Specialist with engineering and neuroscience expertise joins Iconeus team
  • Iconeus funds Ph.D. research into functional ultrasound
  • Iconeus welcomes two new staff in project management and marketing communication
  • New Application Specialist to strengthen ties with neuroscience researchers
  • New staff appointment to enhance in-house software expertise

Careers

• Application Specialist

Publications

• Enhancement of Mediodorsal Thalamus Rescues Aberrant Belief Dynamics in a Novel Mouse Model for Schizophrenia.
• Functional Cerebral Neurovascular Mapping During Focused Ultrasound Peripheral Neuromodulation of Neuropathic Pain.
• Specific and non-uniform brain states during cold perception in mice.
• Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements.
• Circuit mechanism for suppression of frontal cortical ignition during NREM sleep.
• Chronic brain functional ultrasound imaging in freely moving rodents performing cognitive tasks.
• Decoding motor plans using a closed-loop ultrasonic brain-machine interface.
• Functional ultrasound imaging of stroke in awake rats.
• Dissecting Multiparametric Cerebral Hemodynamics using Integrated Ultrafast Ultrasound and Multispectral Photoacoustic Imaging.
• Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part II: Functional Imaging.
• Human brain mapping using co-registered fUS, fMRI and ESM during awake brain surgeries: A proof-of-concept study.
• Commentary to Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke
• Editorial: In vivo functional neuroimaging for pharmacology.
• Swept-3-D Ultrasound Imaging of the Mouse Brain Using a Continuously Moving 1-D-Array-Part I: Doppler Imaging.
• Functional ultrasound reveals effects of MRI acoustic noise on brain function.
• Time-lagged Functional Ultrasound for Multi- parametric Cerebral Hemodynamic Imaging.
• Editorial: Awake functional imaging of small animals.
• Case report: High-resolution, intra-operative µDoppler-imaging of spinal cord hemangioblastoma.
• Functional ultrasound detects frequency-specific acute and delayed S-ketamine effects in the healthy mouse brain.
• Microscale acoustic metamaterials as conformal sonotransparent skull prostheses.
• Filler-Enhanced Piezoelectricity of Poly-L-Lactide and Its Use as a Functional Ultrasound-Activated Biomaterial.
• High-Level Synthesis Design of Scalable Ultrafast Ultrasound Beamformer With Single FPGA.
• Co-variations of cerebral blood volume and single neurons discharge during resting state and visual cognitive tasks in non-human primates.
• Decoding behavior from global cerebrovascular activity using neural networks.
• Functional imaging of the exposed brain.
• Functional ultrasound imaging reveals 3D structure of orientation domains in ferret primary visual cortex.
• Correction to: Deconvolution of the Functional Ultrasound Response in the Mouse Visual Pathway Using Block-Term Decomposition.
• Evaluation of Non-invasive Optogenetic Stimulation with Transcranial Functional Ultrasound Imaging.
• A window to the brain: ultrasound imaging of human neural activity through a permanent acoustic window.
• Brain-wide mapping of resting-state networks in mice using high-frame rate functional ultrasound.
• Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.
• Mapping Pharmacologically Evoked Neurovascular Activation and Its Suppression in a Rat Model of Tremor Using Functional Ultrasound: A Feasibility Study.
• The Emergence of Functional Ultrasound for Noninvasive Brain-Computer Interface.
• Deep-fUS: A Deep Learning Platform for Functional Ultrasound Imaging of the Brain Using Sparse Data
• Impaired Local and Long-Range Brain Connectivity and Visual Response in a Genetic Rat Model of Hyperactivity Revealed by Functional Ultrasound
• Altered Cortical Trigeminal Fields Excitability by Spreading Depolarization Revealed with in Vivo Functional Ultrasound Imaging Combined with Electrophysiology
• Randomized Spatial Downsampling-Based Cauchy-RPCA Clutter Filtering for High-Resolution Ultrafast Ultrasound Microvasculature Imaging and Functional Imaging.
• Covariations between pupil diameter and supplementary eye field activity suggest a role in cognitive effort implementation
• Ultrasonic Methods for Brain Imaging: Techniques and Implications.
• In Vivo Functional Ultrasound (fUS) Real-Time Imaging and Dosimetry of Mice Brain Under Radiofrequency Exposure
• In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy.
• Functional ultrasound imaging of recent and remote memory recall in the associative fear neural network in mice
• Ultrasound localization microscopy and functional ultrasound imaging reveal atypical features of the trigeminal ganglion vasculature
• Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale.
• Active neural coordination of motor behaviors with internal states.
• Cranial window for longitudinal and multimodal imaging of the whole mouse cortex.
• Multiscale imaging informs translational mouse modeling of neurological disease.
• Pharmaco-fUS in cognitive impairment: Lessons from a preclinical model.
• Type 2 diabetes albuminuric and non-albuminuric phenotypes have different morphological and functional ultrasound features of diabetic kidney disease.
• The developments and applications of functional ultrasound imaging.
• Retinal functional ultrasound imaging (rfUS) for assessing neurovascular alterations: a pilot study on a rat model of dementia.
• Deconvolution of the Functional Ultrasound Response in the Mouse Visual Pathway Using Block-Term Decomposition.
• Global dissociation of the posterior amygdala from the rest of the brain during REM sleep.
• High-sensitivity detection of optogenetically-induced neural activity with functional ultrasound imaging
• A functional ultrasound brain GPS for automatic vascular-based neuronavigation
• Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex
• Hemodynamic response to sensory stimulation in mice: Comparison between functional ultrasound and optoacoustic imaging
• Optogenetic fUSI for brain-wide mapping of neural activity mediating collicular-dependent behaviors
• Single-trial decoding of movement intentions using functional ultrasound neuroimaging
• Inter-subject registration and application of the SIGMA rat brain atlas for regional labeling in functional ultrasound imaging
• Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients
• Functional ultrasound imaging: a new imaging modality for neuroscience
• Whole-brain 3D activation and functional connectivity mapping in mice using transcranial functional ultrasound imaging
• Bedside functional monitoring of the dynamic brain connectivity in human neonates
• Imaging the response to deep brain stimulation in rodent using functional ultrasound
• Large-scale functional ultrasound imaging of the spinal cord reveals in-depth spatiotemporal responses of spinal nociceptive circuits in both normal and inflammatory states
• Adaptive modulation of brain hemodynamics across stereotyped running episodes
• Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging
• Functional ultrasound speckle decorrelation-based velocimetry of the brain
• Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice
• Transfer functions linking neural calcium to single voxel functional ultrasound signal
• Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain
• Changes in spinal cord hemodynamics reflect modulation of spinal network with different parameters of epidural stimulation
• 4D Functional imaging of the rat brain using a large aperture row-column array
• Chronic imaging of mouse brain: From optical systems to functional ultrasound
• Ultrafast ultrasound imaging pattern analysis reveals distinctive dynamic brain states and potent sub-network alterations in arthritic animals
• Acoustic biomolecules enhance hemodynamic functional ultrasound imaging of neural activity
• Early ultrafast ultrasound imaging of cerebral perfusion correlates with ischemic stroke outcomes and responses to treatment in mice
• Functional ultrasound imaging of deep visual cortex in awake nonhuman primates
• Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors
• A large aperture row column addressed probe for in vivo 4D ultrafast doppler ultrasound imaging
• Ultrafast doppler for neonatal brain imaging
• 4D Functional ultrasound imaging of whole-brain activity in rodents
• Functional ultrasound imaging of the brain reveals propagation of task-related brain activity in behaving primates
• Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia
• Functional Ultrasound Imaging of Spinal Cord Hemodynamic Responses to Epidural Electrical Stimulation: A Feasibility Study
• Microvascular flow dictates the compromise between spatial resolution and acquisition time in ultrasound localization microscopy
• Local hippocampal fast gamma rhythms precede brain-wide hyperemic patterns during spontaneous rodent REM sleep
• 3D functional ultrasound imaging of pigeons
• Whole-brain functional ultrasound imaging reveals brain modules for visuomotor integration
• Multi-parametric functional ultrasound imaging of cerebral hemodynamics in a cardiopulmonary resuscitation model
• Evidence from functional ultrasound imaging of enhanced contralesional microvascular response to somatosensory stimulation in acute middle cerebral artery occlusion/reperfusion in rats: A marker of ultra-early network reorganization?
• Ultrasound localization microscopy and super-resolution: A state of the art
• Adaptive spatiotemporal SVD clutter filtering for ultrafast doppler imaging using similarity of spatial singular vectors
• Multi-scale mapping along the auditory hierarchy using high-resolution functional ultrasound in the awake ferret
• Functional ultrasound neuroimaging: A review of the preclinical and clinical state of the art
• Functional ultrasound imaging of brain activity in human newborns
• Intraoperative functional ultrasound imaging of human brain activity
• Transcranial functional ultrasound imaging in freely moving awake mice and anesthetized young rats without contrast agent
• 3D Functional ultrasound imaging of the cerebral visual system in rodents
• Subwavelength motion-correction for ultrafast ultrasound localization microscopy
• Light controls cerebral blood flow in naive animals
• Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction
• Simultaneous recording of neuronal and vascular dynamics in mobile animals
• Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
• 4D Microvascular imaging based on ultrafast doppler tomography
• Resolution limits of ultrafast ultrasound localization microscopy
• Multiplane wave imaging increases signal-to-noise ratio in ultrafast ultrasound imaging
• Transcranial functional ultrasound imaging of the brain using microbubble-enhanced ultrasensitive doppler
• EEG and functional ultrasound imaging in mobile rats
• Spatiotemporal clutter filtering of ultrafast ultrasound data highly increases doppler and fultrasound sensitivity
• Functional ultrasound imaging of intrinsic connectivity in the living rat brain with high spatiotemporal resolution
• Functional ultrasound imaging reveals different odor-evoked patterns of vascular activity in the main olfactory bulb and the anterior piriform cortex
• Ultrafast doppler reveals the mapping of cerebral vascular resistivity in neonates
• Ultrafast imaging in biomedical ultrasound [Review]
• Functional ultrasound imaging of the brain: Theory and basic principles
• Imaging of perfusion, angiogenesis, and tissue elasticity after stroke
• Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine
• Pharmaco-fUS for characterizing drugs for Alzheimer’s disease – The case of THN201, a drug combination of Donepezil plus Mefloquine
• Functional ultrasound imaging of the brain